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Prostate cancer research

The prostate is a small gland, about the size of a walnut, found only in men. It lies at the base of the bladder and surrounds the urethra, the tube that carries urine out of the body.Prostate cancer is the most common cancer in men in the UK. Each year, around 37,000 new cases of prostate cancer are diagnosed in the UK and the disease claims around 10,400 lives.

Cancer Research UK is the largest funder of prostate cancer research in the UK. We fund research at all levels, from uncovering the disease’s causes to developing new treatments. Read more about our impact on prostate cancer over the years.

Below are some of the highlights of our prostate cancer research portfolio. Visit MyProjects to donate directly to our research into the disease.

Or find out more on our prostate cancer briefsheet.

Cancer biology

Dr David Waugh Dr David Waugh

Centre for Cancer Research and Cell Biology

Queen’s University Belfast, Belfast

Improving radiotherapy treatment for prostate cancer

Although survival from prostate cancer is improving, the disease still claims thousands of lives every year in the UK. At Queen’s University Belfast, Dr David Waugh is investigating why some prostate cancers don’t respond well to radiotherapy. He hopes his research will reveal new ways of improving this mainstay treatment so that more men’s lives can be saved.

Cancer genes

Prof Doug Easton Prof Doug Easton

Cancer Research UK Genetic Epidemiology Group

University of Cambridge, Cambridge

Hunting cancer susceptibility genes

Professor Douglas Easton is director of the Cancer Research UK Genetic Epidemiology Group at the University of Cambridge. He is world-renowned for his research into genes that affect our risk of common cancers, particularly breast cancer. His team also works on ovarian and prostate cancer, and melanoma. Their findings will help identify high-risk individuals and could lead to new ways of preventing, diagnosing and treating the disease in the future.

Professor Ros Eeles Professor Ros Eeles

Section of Cancer Genetics

The Institute of Cancer Research, London

Studying prostate and breast cancer genes

Professor Ros Eeles at the Institute of Cancer Research in Sutton is studying prostate and breast cancer genetics. She is also involved in helping to evaluate the NHS breast screening programme, ensuring that the service continues to improve. 

Prof David Neal Prof David Neal

Oncology Department, Addenbrooke's Hospital

University of Cambridge, Cambridge

Better screening and treatment for prostate cancer

Professor David Neal is surgeon and a leading expert on prostate cancer. He and his colleagues in Cambridge are taking a number of different approaches in their work to beat this disease. A particular focus for the team is identifying better ways of distinguishing aggressive cancers from non-aggressive cancers in order to target treatment to the right group of men. Professor Neal is also investigating the genes involved in prostate and bladder cancer.

Cancer spread (metastasis)

Professor Peter Croucher Professor Peter Croucher

Academic Unit of Bone Biology
University of Sheffield Medical School

University of Sheffield, Sheffield

Understanding why cancer spreads to the bones

Professor Peter Croucher is a respected expert in bone research, based at the University of Sheffield. He and his team are investigating how some cancers spread into the bones. This is common in breast and prostate cancers, and once it happens, the disease becomes difficult to treat successfully. Understanding why tumours spread and how to stop them is vital to help beat cancer.

Clinical trials

Prof Nick James Prof Nick James

School of Cancer Sciences

University of Birmingham, Birmingham

Improving prostate cancer treatment

Professor Nick James is Professor of Clinical Oncology at the University of Birmingham and also Consultant in Clinical Oncology at the city's Queen Elizabeth Hospital. He is carrying out an important 8-year long trial looking at the use of hormone treatment for prostate cancer.

Drug discovery & development

Prof Gareth Williams Prof Gareth Williams

Cancer Research UK Chromosomal Replication Research Group

Wolfson Institute for Biomedical Research, University College London, London

Understanding how cells divide, and improving cancer treatment and detection

Based at the Wolfson Institute for Biomedical Research in London, Professor Gareth Williams and his team are investigating how a group of proteins work together to allow DNA to be copied, a process called DNA replication. His research could also help to find new ways to diagnose cancers such as prostate and bladder cancer.

Hormone therapy

Prof Nick James Prof Nick James

School of Cancer Sciences

University of Birmingham, Birmingham

Improving prostate cancer treatment

Professor Nick James is Professor of Clinical Oncology at the University of Birmingham and also Consultant in Clinical Oncology at the city's Queen Elizabeth Hospital. He is carrying out an important 8-year long trial looking at the use of hormone treatment for prostate cancer.

Prof David Neal Prof David Neal

Oncology Department, Addenbrooke's Hospital

University of Cambridge, Cambridge

Better screening and treatment for prostate cancer

Professor David Neal is surgeon and a leading expert on prostate cancer. He and his colleagues in Cambridge are taking a number of different approaches in their work to beat this disease. A particular focus for the team is identifying better ways of distinguishing aggressive cancers from non-aggressive cancers in order to target treatment to the right group of men. Professor Neal is also investigating the genes involved in prostate and bladder cancer.

Radiotherapy

Dr David Waugh Dr David Waugh

Centre for Cancer Research and Cell Biology

Queen’s University Belfast, Belfast

Improving radiotherapy treatment for prostate cancer

Although survival from prostate cancer is improving, the disease still claims thousands of lives every year in the UK. At Queen’s University Belfast, Dr David Waugh is investigating why some prostate cancers don’t respond well to radiotherapy. He hopes his research will reveal new ways of improving this mainstay treatment so that more men’s lives can be saved.

Screening

Prof David Neal Prof David Neal

Oncology Department, Addenbrooke's Hospital

University of Cambridge, Cambridge

Better screening and treatment for prostate cancer

Professor David Neal is surgeon and a leading expert on prostate cancer. He and his colleagues in Cambridge are taking a number of different approaches in their work to beat this disease. A particular focus for the team is identifying better ways of distinguishing aggressive cancers from non-aggressive cancers in order to target treatment to the right group of men. Professor Neal is also investigating the genes involved in prostate and bladder cancer.

Prof Gareth Williams Prof Gareth Williams

Cancer Research UK Chromosomal Replication Research Group

Wolfson Institute for Biomedical Research, University College London, London

Understanding how cells divide, and improving cancer treatment and detection

Based at the Wolfson Institute for Biomedical Research in London, Professor Gareth Williams and his team are investigating how a group of proteins work together to allow DNA to be copied, a process called DNA replication. His research could also help to find new ways to diagnose cancers such as prostate and bladder cancer.

Surgery

Professor Ara Darzi Professor Ara Darzi

Division of Surgery

Imperial College, London

Saving more lives through surgery

Based at Imperial College, London, Professor Ara Darzi is one of the world’s leading surgeons and a pioneer of keyhole surgery. He is investigating robotic surgery and other techniques that will improve the outlook for cancer patients in London and across the UK.