Dr David Tuveson
Tumour Modelling & Experimental Medicine
Cancer Research UK Cambridge Research Institute
Cambridge
New ways to treat pancreatic cancer
Dr David Tuveson is a leading expert investigating the biology and treatment of pancreatic cancer. He is and his team at Cancer Research UK’s Cambridge Research Institute are using the latest genetic techniques to find new ways to treat the disease. Pancreatic cancer has been recognised by Cancer Research UK as an area that urgently needs more research, and Dr Tuveson’s work will help to meet our goal of improving survival.
Dr Tuveson and his team are studying pancreatic cancer in the lab to find clues for ways to treat the disease. Understanding how cells in the pancreas go wrong and develop into cancer is a crucial step towards developing new treatments that can help to save lives.
One of the team’s new treatments targets a protein called Notch, which is involved in the development and growth of pancreatic tumours. The researchers have tested a drug that blocks the action of this protein, with promising results. Dr Tuveson now plans to test a similar drug in patients with pancreatic cancer.
Clinical trials
In order to test new treatments like this, Dr Tuveson is setting up a clinical trials unit at Addenbrooke’s Hospital in Cambridge. Clinical trials are vital for finding new, effective ways to treat cancer, and Dr Tuveson’s research will help to save more lives in the future.

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