Prof Trevor Dale

Trevor Dale

School of Biosciences
Cardiff University
Cardiff

Studying gene faults involved in liver and bowel cancer

Professor Trevor Dale and his team at the University of Cardiff are investigating faults in important genes that can lead to bowel or liver cancer. By understanding more about these faulty genes, Professor Dale's work is paving the way for new treatments for these diseases.

Studying cancer genes in the lab

Professor Dale and his team are investigating specific genes involved in liver and bowel cancer. In particular, they are focusing on Axin genes, which are damaged or missing in many liver cancers and some bowel cancers.

By artificially removing Axin genes from liver and bowel cells, the researchers can study in precise detail how this leads to cancer. For example, they will be looking at other genes that interact with Axin genes, to see how they are affected when it is missing.

Working towards new treatments

Through Professor Dale's research, we will gain a deeper understanding of how faulty genes lead to bowel or liver cancer. And by knowing more about the biological processes involved, scientists will be able to develop more effective treatments for these diseases in the future.

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