Our research in Cardiff
Cardiff is the home of one of our new Cancer Research UK Centres. The Cardiff Centre will help set the pace for national and international progress in genetics and cancer biomarkers. Researchers at the Centre will be focusing on the biology and treatment of bowel, breast and urological cancers and leukaemia. They will also be working on how to make sure cancer is detected earlier.
Cancer Research UK will be increasing its contribution to research in Cardiff by spending an extra £2 million over three years - a massive boost to keep Cardiff leading the way on cancer research in Wales.
Listen to an interview with Professor Alan Clarke, director of the new centre:
Cancer Research UK provides funding for the Wales Cancer Trials Network based in Cardiff. The network provides direct support to 18 hospitals across Wales, and aims to boost the number of people with cancer taking part in clinical trials.
We also fund the clinical trials work of the Children’s Cancer and Leukaemia Group (CCLG) at the Children's Hospital for Wales in Cardiff. The group co-ordinates the care of virtually all the UK’s children with cancer, ensuring they receive the most up-to-date treatments.
Below are some of the highlights of our research in Cardiff.
Bowel cancer
Prof Alan Clarke
The Genetics Group, School of Biosciences
Cardiff University, Cardiff
Understanding how bowel cancer develops
Professor Alan Clarke at Cardiff University is studying how bowel cancer develops. His research focuses on the role of the APC gene, which is found to be faulty in many cases of bowel cancer.
Prof Tim Maughan
Section of Medicine
Cardiff University, Cardiff
Clinical trials in Wales
Tim Maughan is Professor of Cancer Studies in the School of Medicine at Cardiff University. His research focuses on the treatment of people with bowel cancer. He is currently leading a clinical trial called COIN, which is looking at new treatments for bowel cancer that has spread to other parts of the body.
Breast cancer
Prof Glyn Elwyn
School of Medicine
Cardiff University, Cardiff
The digital age of decision-making
Professor Glyn Elwyn at Cardiff University is pioneering the development of 'online decision explorers' for breast and prostate cancer. These tools will help people make difficult decisions relating to cancer diagnosis and treatment. The questions, information and video clips that make up these web-based aids are designed to guide people through the different options available. By helping people to make well-informed choices, they have the potential to relieve anxiety and improve the well-being of people faced with these life-changing situations.
Liver cancer
Prof Trevor Dale
School of Biosciences
Cardiff University, Cardiff
Studying gene faults involved in liver and bowel cancer
Professor Trevor Dale and his team at the University of Cardiff are investigating faults in important genes that can lead to bowel or liver cancer. By understanding more about these faulty genes, Professor Dale's work is paving the way for new treatments for these diseases.
Lung cancer
Dr Fergus Macbeth
Velindre Hospital
Velindre NHS Trust, Cardiff
Reducing blood clots in lung cancer patients
Dr Fergus Macbeth is an expert in lung cancer research and works at the Velindre Hospital in Cardiff. He is co-ordinating a clinical trial called FRAGMATIC, investigating whether the blood thinning drug Dalteparin (also called Fragmin) can reduce the number of blood clots in people with lung cancer. Blood clots are common in people with the disease and can also be a side effect of treatment. They can be very serious if they start to move through the body so it is important to find ways of preventing them.
Oesophageal cancer
Dr Tom Crosby
Velindre Cancer Centre
Velindre NHS Trust, Cardiff
Testing a new way to treat oesophageal cancer
Dr Tom Crosby is a consultant clinical oncologist at the Velindre Hospital in Cardiff. He is running a clinical trial called SCOPE 1, testing a new way of treating oesophageal cancer (cancer of the foodpipe).
Prostate cancer
Prof Glyn Elwyn
School of Medicine
Cardiff University, Cardiff
The digital age of decision-making
Professor Glyn Elwyn at Cardiff University is pioneering the development of 'online decision explorers' for breast and prostate cancer. These tools will help people make difficult decisions relating to cancer diagnosis and treatment. The questions, information and video clips that make up these web-based aids are designed to guide people through the different options available. By helping people to make well-informed choices, they have the potential to relieve anxiety and improve the well-being of people faced with these life-changing situations.
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