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Our research in Sheffield

UK map showing SheffieldSheffield is home to one of our Cancer Research UK Centres, which brings together researchers, doctors and nurses in the city, promoting collaboration to improve the lives of people with cancer.

Researchers in the Centre are concentrating on breast and lung cancers, with a strong focus on cancers that spread to the bones. They are also studying the fundamental biology of cancer - understanding how the disease starts and how it grows and spreads. You can find out more about the Sheffield Centre on our website.

Watch a video explaining how the launch of the new Centre will benefit research and patients in the city:

Our Children's Cancer Trials Team co-ordinates groundbreaking trials in 21 centres across the UK and Ireland, including the Sheffield Children's Hospital. These trials bring cutting-edge science from the lab to the bedside, making innovative new treatments available to children with cancer.

Below are some of the highlights of our research in Sheffield.

Click on the names below to find out more about each scientist

These pages contain highlights of the research we fund in this city - we'll be updating and expanding them regularly. Please visit our Funding & Research website for detailed scientific information about our research.

Brain tumours

Dr Verdon Taylor Dr Verdon Taylor

Department of Biomedical Science

University of Sheffield, Sheffield

Understanding cells at the root of brain tumours

Dr Verdon Taylor is based at the University of Sheffield. He is studying special cells called stem cells, which researchers think may be the root cause of some cancers. Dr Taylor is focusing on a type of brain tumour called glioma, and his work could lead to innovative new ways to tackle this disease.

Breast cancer

Dr Lisa Caldon Dr Lisa Caldon

Academic Surgical Oncology Unit

University of Sheffield, Royal Hallamshire Hospital, Sheffield

Factors that influence the treatment of women with breast cancer

Dr Lisa Caldon is a breast cancer surgeon working at the Royal Hallamshire Hospital in Sheffield. She is investigating the factors that influence the treatment of breast cancer, and how women choose between the different surgical options.

Professor Peter Croucher Professor Peter Croucher

Academic Unit of Bone Biology
University of Sheffield Medical School

University of Sheffield, Sheffield

Understanding why cancer spreads to the bones

Professor Peter Croucher is a respected expert in bone research, based at the University of Sheffield. He and his team are investigating how some cancers spread into the bones. This is common in breast and prostate cancers, and once it happens, the disease becomes difficult to treat successfully. Understanding why tumours spread and how to stop them is vital to help beat cancer.

No specific cancer type

Professor Claire Lewis Professor Claire Lewis

Inflammation and Tumour Targeting

University of Sheffield Medical School, Sheffield

Linking low oxygen levels to tumour growth

Professor Claire Lewis is studying how low oxygen levels within a tumour, known as hypoxia, can encourage it to grow and spread. In particular, she is investigating whether hypoxia in tumours attracts special immune cells called macrophages, which can encourage this process.

Prof Gillian Tozer Prof Gillian Tozer

Tumour Microcirculation group

University of Sheffield, Sheffield

Targeting the blood supply in tumours

Professor Gillian Tozer runs the Tumour Microcirculation Group at the University of Sheffield. She and her team are investigating the way that blood vessels grow within a tumour - a process known as angiogenesis.  They are seeking new ways of targeting this process in order to develop better treatments for cancer.

Prostate cancer

Professor Peter Croucher Professor Peter Croucher

Academic Unit of Bone Biology
University of Sheffield Medical School

University of Sheffield, Sheffield

Understanding why cancer spreads to the bones

Professor Peter Croucher is a respected expert in bone research, based at the University of Sheffield. He and his team are investigating how some cancers spread into the bones. This is common in breast and prostate cancers, and once it happens, the disease becomes difficult to treat successfully. Understanding why tumours spread and how to stop them is vital to help beat cancer.