UK Brain and Central Nervous System Cancer incidence statistics

UK Brain and Central Nervous System Cancer incidence statistics

This page contains brain cancer incidence statistics with information by age, and trends over time.The ICD code for brain and other central nervous system cancers is ICD9 191-192 and ICD10 C70-72.

Primary cancer of the brain is rare. In 2006 there were 4,532 new cases of brain or central nervous system cancers diagnosed, around 7 per 100,000 population. 1-4 A GP will see, on average, four new patients with primary brain tumours during their career. Although brain tumours account for less than 2% of all primary tumours they are responsible for 7% of the years of life lost from cancer before age 70. 5

It has been estimated that the lifetime risk of developing brain and cns cancer is 1 in 133 for men and 1 in 185 for women in the UK. These were calculated in February 2009 using incidence and mortality data for 2001-2005. 6

Table 1.1 shows the number of new cases and incidence rates for brain and central nervous system cancers by sex for the UK and its constituent countries.

Table showing the number of new cases and rates of brain and other CNS tumours, UK, 2006

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Brain and central nervous system cancer incidence by age

Brain tumours occur at any age and represent the commonest site for solid tumours in childhood. A small peak in incidence of brain tumours in early childhood drops to a poorly defined minimum in teenage years rising to a second major peak in people in their 70s as Figure 1.1 shows. The decline after age 75 may be an artefact of data collection. The tumour type and site vary with age with clear distinctions between adult and childhood brain tumours. Most childhood brain tumours (70 - 80%) arise infratentorially (glial tumours, medulloblastoma) or in the midline (germ cell tumours, craniopharyngioma). Glial tumours in children are more frequently low grade c. In adults most brain tumours are supratentorial where high grade gliomas and meningiomas predominate.

Chart showing the number of new cases and age-specific incidence rates, by sex, for brain and CNS tumrous in the UK, 2006

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Brain and central nervous system cancer incidence trends

Interpretation of brain and central nervous system cancer incidence trends over time is difficult for several reasons including changes in coding practices and coding classifications, and the introduction of new more accurate diagnostic techniques. In Great Britain the age-standardised incidence rates for brain and central nervous system cancers have increased slightly between 1975 and 2006 as shown in Figure 1.2 but much of this increase is confined to the over-65s.

Chart showing the age-stadardised (European) incidence rates for brain and CNS tumours, by sex, for Great Britain, 1975-2006

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What proportion of the increase is artefactual rather than real is uncertain and it has been suggested that the introduction of computed tomography scanning in the 1970s and magnetic resonance imaging in the 1980s is likely to account for a substantial proportion of the increase, particularly at older ages. Some specific types of brain tumours are said to be increasing in incidence for example, gliomas in the elderly and lymphomas in both immune competent and incompetent patients.

UK brain and central nervous system tumours incidence trends are shown in Figure 1.3.

Chart showing the age standardised (European) incidence rates for brain and CNS tumours, by sex, for the UK, 1996-2006

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Updated: 14/07/2008 0:00

UK Brain and central nervous system cancer mortality statistics

This page presents brain and central nervous system cancer mortality statistics including by age and sex and trends over time.

In 2007, in the UK there were 3,611 deaths from brain and other central nervous system cancers, which accounted for just over 2% of all cancer deaths. The annual number of deaths in the UK and its constituent countries together with the rates for the year 2007 are shown in Table 2.11-4.

Table 2.1: Number of deaths and mortality rates of brain and other central nervous system cancer, UK

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Brain and central nervous system tumour mortality by age and sex

The distribution of deaths from brain and central nervous system tumours by age for males and females separately are shown in Figure 2.11-4.

Figure 2.1: Numbers of deaths and age-specific mortality rates brain and central nervous system cancer, by sex, UK

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Trends in brain and central nervous system cancers mortality

The age-standardised mortality rates for brain and central nervous system tumours between 1971 and 2007 for the UK are shown in Figure 2.2.

Figure 2.2: Age-standardised (European) mortality, brain and central nervous system cancer, by sex, UK

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Updated: 30/04/2009 0:00

Brain and Central Nervous System Cancer survival statistics

This page presents brain and central nervous system (CNS) cancer survival statistics. Data is presented as one, five and ten year, survival from year of diagnosis, and survival by age at diagnosis.

Brain and CNS cancer - one year survival rates

Figure 3.1 shows one year survival rates for brain and other central nervous system tumours.

Figure 3.1: One-year age-standardised survival for brain cancer by sex for patients diagnosed in England and Wales during 1971-1999

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Brain and CNS cancer - five year survival rates

Figure 3.2 shows five year survival rates for brain and other central nervous system tumours.

Figure 3.2: Five-year age-standardised survival for brain cancer by sex for patients diagnosed in England and Wales during 1971-1999

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Brain and CNS cancer - ten year survival rates

Figure 3.3 shows ten year survival rates for brain and other central nervous system tumours.

Figure 3.3: Ten-year age-standardised survival for brain cancer by sex for patients diagnosed in England and Wales during 1971-1999

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Brain cancer survival rates by age

Figure 3.4 shows five year survival rates for brain and other central nervous system tumours by age at diagnosis.

Figure 3.4: Five-year relative survival for patients diagnosed with brain cancer in England and Wales during 1986-1990 by age at diagnosis

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Updated: 30/12/2004 0:00

References

UK Brain and Central Nervous System Cancer incidence statistics

  1.  Office for National Statistics, Cancer Statistics registrations: Registrations of cancer diagnosed in 2006, England. Series MB1 no.37. 2009, National Statistics: London.
  2.  Welsh Cancer Intelligence and Surveillance Unit, 2009. Cancer Registrations in Wales 2006
  3.  ISD Scotland. 2009, Information and Statistics Division, NHS Scotland.
  4.  Northern Ireland Cancer Registry, Cancer Incidence and Mortality. 2009
  5.  Holman C, Hatton W, Armstrong B, English D., Cancer mortality trends in Australia.Vol 2, 1910-1984. Health Department, Western Australia, Perth. 1987
  6.  Statistical Information Team, Cancer Research UK. 2009

UK Brain and central nervous system cancer mortality statistics

  1.  Office for National Statistics. Mortality Statistics, England and Wales, 2007. Accessed 2009
  2.  Scottish Health Statistics 2007 ISD Scotland Accessed 2009
  3.  Welsh Cancer Intelligence and Surveillance Unit. Cancer Mortality in Wales 2007. Accessed 2009
  4.  Northern Ireland Cancer Registry. Cancer Mortality in Northern Ireland, 2007. Accessed 2008

Brain and Central Nervous System Cancer survival statistics

  1. Coleman, M.P., et al., Cancer Survival Trends in England & Wales, 1971-1995 Deprivation & NHS Region. The Stationery Office.
  2. Coleman, M.P., et al., Trends and socioeconomic inequalities in cancer survival in England and Wales up to 2001. Br J Cancer, 2004. 90(7):p. 1367-73.